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Integrin alpha-6 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 27189-1-AP-20UL
Additional Details : Weight : 0.00010kg
Description
E3 ubiquitin-protein ligase that mediates the ubiquitination of p53/TP53 in the late response to DNA damage, and acts as a positive regulator of p53/TP53 stability, thereby regulating the G1/S DNA damage checkpoint. May act by catalyzing the formation of short polyubiquitin chains on p53/TP53 that are not targeted to the proteasome. In response to ionizing radiation, interacts with MDM2 and enhances p53/TP53 ubiquitination, possibly by restricting MDM2 from extending polyubiquitin chains on ubiquitinated p53/TP53. Plays a role in RPA-mediated DNA damage signaling and repair.Specifications
| Integrin alpha-6 | |
| Polyclonal | |
| Unconjugated | |
| ITGA6 | |
| CD49f, Integrin alpha 6, Integrin alpha-6, integrin, alpha 6, ITGA6, ITGA6B, VLA 6 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 3655 | |
| -20°C | |
| Liquid |
| Western Blot, Immunohistochemistry (Paraffin) | |
| 0.23 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| P23229 | |
| ITGA6 | |
| Integrin alpha-6 Fusion Protein Ag25835 | |
| 20 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |