Necessary for the complete degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA fragments shorter than 10 nucleotides that are produced by 3′->5′ exosome-mediated mRNA decay. Releases m7GMP. Can also degrade m7GDP to m7GMP. Has no activity towards mRNA molecules longer than 25 nucleotides.
5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase; DCS-1; Decapping scavenger enzyme; heat shock-like protein 1; HINT-5; HINT-5 HSL1 DCS-1 heat shock-like protein 1 hint-related 7meGMP-directed hydrolase histidine triad protein member 5 homolog of C. elegans 7meGMP-directed hydrolase dcs-1 mRNA decapping enzyme scavenger mRNA-decapping enzyme DcpS; Hint-related 7meGMP-directed hydrolase; Histidine triad nucleotide-binding protein 5; Histidine triad protein member 5; homolog of C. elegans 7meGMP-directed hydrolase dcs-1; m7GpppX diphosphatase; mRNA decapping enzyme; Scavenger mRNA-decapping enzyme DcpS
Cat # 15706741
100 µL
Cat # 16168882
100 µg
Cat # 15995774
100 µL
Cat # 13405067
100 µL
Cat # 16576181
100 µL
Cat # 16165966
100 µg
Cat # 15985724
100 µL
Cat # 13465027
100 µL
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