Clathrin (see MIM 118955)-mediated endocytosis is a majormechanism for internalization of proteins and lipids. Members ofthe connecdenn family, such as DENND1B, function as guaninenucleotide exchange factors (GEFs) for the early endosomal smallGTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptorprotein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35activation with the clathrin machinery.
Connecdenn 2; DENN domain-containing protein 1B; DENN/MADD domain containing 1B; family with sequence similarity 31, member B; Protein FAM31B; RP11-53I24.2 C1ORF18 C1orf218 FAM31B DENN domain-containing protein 1B connecdenn 2 family with sequence similarity 31 member B
Cat # 15717881
100 µL
Cat # 13267288
400 µL
Cat # 16196759
50 µg
Cat # 16186759
50 µL
Cat # 13299808
100 µL
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