CD358 / DR6 (Death Receptor-6) is a type I transmembrane protein of the TNF receptor superfamily, expressed in most human tissues and able of inducing apoptosis through its cytoplasmic death domain. Unlike TNFR1 and Fas, DR6 induces apoptosis independently of FADD adaptor. In immune system, DR6 serves as an important regulator for CD4+ T cell proliferation and Th differentiation, and provides also a regulatory mechanism for B cell activation and humoral immune responses.
CD358; Death receptor 6; Death receptor-6; TNFR-related death receptor 6; Tumor necrosis factor receptor superfamily member 21; tumor necrosis factor receptor superfamily, member 21
Cat # 16384714
100 µL
Cat # 12878142
100 µg
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100 µL
Cat # 16898915
150 µL
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100 µL
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20 µL
Cat # 16398134
100 µL
Cat # 16374714
100 µL
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