Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 for DAP kinase-related apoptosis-inducing protein kinases1. DRAKs contain an N-terminal kinase domain and a C-terminal regulation domain. Overexpression of DRAK1 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. DRAK1 is located in ...
Cat # 16360205
100 µL
Cat # 15913785
100 µL
Cat # 11317113
100 µg
Cat # 15764756
0.1 mg
Cat # 15768154
25 ug
Cat # 11514991
100 µL
Cat # 13471456
100 ug
Cat # 12848142
100 µg
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