This gene is a member of the MAD gene family. The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues.
bHLHc12; Class C basic helix-loop-helix protein 12; Mad4 homolog; Max dimerization protein 4; Max dimerizer 4; Max-associated protein 4; Max-interacting transcriptional repressor MAD4; MXD4 MAD4 MAX dimerization protein 4 Mad4 homolog MST149 MSTP149 bHLHc12
Cat # 15926664
100 µL
Cat # 15514272
100 µL
Cat # 11386063
100 µg
Cat # 15956654
100 µL
Cat # 17197923
100 µL
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