Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for cholesterol-dependent gene regulation. Positively regulates the Nodal signaling pathway.
Activator-recruited cofactor 105 kDa component; activator-recruited cofactor, 105-kD; ARC105; CTG repeat protein 7a; Mediator complex subunit 15; Mediator of RNA polymerase II transcription subunit 15; Mediator of RNA polymerase II transcription subunit 15 Activator-recruited cofactor 105 kDa component ARC105 CTG repeat protein 7a Mediator complex subunit 15 Positive cofactor 2 glutamine/Q-rich-associated protein PC2 glutamine/Q-rich-associated protein TPA-inducible gene 1 protein TIG-1 Trinucleotide repeat-containing gene 7 protein; PC2 (positive cofactor 2, multiprotein complex) glutamine/Q-rich-associated protein; PC2 glutamine/Q-rich-associated protein; PC2-glutamine-rich-associated protein; Positive cofactor 2 glutamine/Q-rich-associated protein; positive cofactor 2, glutamine/Q-rich-associated protein; positive cofactor 2, multiprotein complex, glutamine/Q-rich-associated protein; TIG-1; TPA inducible gene-1; TPA inducible protein; TPA-inducible gene 1 protein; trinucleotide repeat containing 7; Trinucleotide repeat-containing gene 7 protein
Cat # 15945225
100 µg
Cat # 15674775
100 µL
Cat # 17239313
100 µL
Cat # 11397053
100 µg
Cat # 16660365
100 µL
Cat # 15926524
100 µL
Cat # 15986514
100 µL
Cat # 16511532
100 µg
Cat # 15769800
100 µL
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