PDGFRA is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.
Alpha platelet-derived growth factor receptor; Alpha-type platelet-derived growth factor receptor; CD140 antigen-like family member A; CD140a; CD140a antigen; PDGF Receptor alpha MGC74795 PDGFR2 RHEPDGFRA CD140 antigen-like family member A CD140a antigen PDGF-R-alpha PDGFRA/BCR fusion pdgfr-a; PDGF-R-alpha; PDGFR-2; PDGFRA/BCR fusion; Platelet-derived growth factor alpha receptor; Platelet-derived growth factor receptor 2; Platelet-derived growth factor receptor alpha; platelet-derived growth factor receptor, alpha polypeptide; rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein
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100 tests
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500 µL
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100 ug
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100 Tests
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100 Reactions
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400 uL
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100 µL
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100 µg
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100 µL
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400 uL
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500 µL
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500 µL
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50 µg
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150 µL
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100 µL
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100 µg
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100 µg
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100 ug
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400 uL
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100 µL
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100 µg
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100 Reactions
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100 Tests
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20 µL
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400 uL
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