CAS RN 1029044-16-3
CAS RN 1029044-16-3
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Tocris Bioscience™ Pexidartinib
Potent CSF-1R inhibitor
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Pexidartinib, MedChemExpress
MedChemExpress Pexidartinib (PLX-3397) is a potent, orally active, selective, and ATP-competitive colony stimulating factor 1 receptor (CSF1R or M-CSFR) and c-Kit inhibitor, with IC50s of 20 and 10 nM, respectively. Pexidartinib (PLX-3397) exhibits 10- to 100-fold selectivity for c-Kit and CSF1R over other related kinases. Pexidartinib (PLX-3397) induces cell apoptosis and has anti-tumor activity.
