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Significant events in Cell Biology

1658

Jan Swammerdam, Dutch doctor and naturalist, first observed and described the red blood cells under a microscope. [1]

1676

Anton van Leeuwenhoek reported the discovery of micro-organisms.[2]

1838

German Botanist Matthias Schleiden discovered that plants are made of cells

1839

German zoologist, Theodor Schwann discovered that animals are made of cells

1858

German physician named Rudolph Virchow discovered that cells only arise from pre-existing cells

1892

Hans Driesch separated the individual cells of a 2-cell sea urchin embryo and shows that each cell develops into a complete individual, thus disproving the theory of preformation and showing that each cell is "totipotent," containing all the hereditary information necessary to form an individual.

1926

Svedberg developed the first analytical ultracentrifuge.

1931

Ruska builds the first Transmission Electron Microscope.

1941

Coons used fluorescent labeled antibodies to detect cellular antigens.

1952

Gey and co-workers established a continuous human cell line.

1965

First commercial Scanning Electron Microscope produced.


  1. Biblia Naturae (2011, reproduction of a book published before 1923, by Jan Swammerdam (Author) , Herman Boerhaave (Author) , Hieronymus David Gaubius (Creator), Nabu Press, ISBN-10: 1272225054
  2. Landmark Papers in Cell Biology: Selected Research Articles Celebrating Forty Years of The American Society for Cell Biology. 2000. Cold Spring Harbor Laboratory Press.

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