CAS RN 1223001-51-1
IUPAC Namn:
9-(6-aminopyridin-3-yl)-1-[3-(trifluoromethyl)phenyl]-1H,2H-benzo[h]1,6-naphthyridin-2-one
Synonymer:
9-(6-aminopyridin-3-yl)-1-[3-(trifluoromethyl)phenyl]benzo[h]1,6-naphthyridin-2-one
Molekylvikt (g/mol):
432.41
Molekylär sammansättning:
C24H15F3N4O
InChi Key:
GUXXEUUYCAYESJ-UHFFFAOYSA-N
SMILES:
NC1=NC=C(C=C1)C1=CC=C2N=CC3=C(N(C(=O)C=C3)C3=CC=CC(=C3)C(F)(F)F)C2=C1
1
–
4
av
4
Resultat
1
Tocris Bioscience™ Torin 2
CAS: 1223001-51-1 Molekylformel: C24H15F3N4O
2
Torin 2, TRC
High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.
3
Torin 2, MedChemExpress
MedChemExpress Torin 2 is an mTOR inhibitor with EC50 of 0.25 nM for inhibiting cellular mTOR activity, and exhibits 800-fold selectivity over PI3K (EC50: 200 nM). Torin 2 also inhibits DNA-PK with an IC50 of 0.5 nM in the cell free assay. Torin 2 can suppress both mTORC1 and mTORC2.
4