CAS RN 1234015-54-3

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Prexasertib dihydrochloride, MedChemExpress

MedChemExpress Prexasertib dihydrochloride (LY2606368 dihydrochloride) is a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor with a Ki of 0.9 nM and an IC50 of 50=8 nM) and RSK1 (IC50=9 nM). Prexasertib dihydrochloride causes double-stranded DNA breakage and replication catastrophe resulting in apoptosis. Prexasertib dihydrochloride shows potent anti-tumor activity.

Prissättning och tillgänglighet
Specifikationer

Molekylformel	C₁₈H₂₁Cl₂N₇O₂
Rekommenderad förvaring	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Formel vikt	438.31
Hållbarhet	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Löslighetsinformation	DMSO : 8 mg/mL (18.25 mM; Need ultrasonic) ∣H2O : 1 mg/mL (2.28 mM; ultrasonic and warming and heat to 80°C)
Anteckningar om renhetsgrad	Research
Fysisk form	Solid
Kvalitet	Research
Färg	Yellow
CAS	1234015-54-3
LEDER	NCCCOC(C=CC=C1OC)=C1C2=CC(NC3=NC=C(C#N)N=C3)=NN2.[H]Cl.[H]Cl
Molekylvikt (g/mol)	438.31
Synonym	LY2606368 dihydrochloride
Kemiskt namn eller material	Prexasertib dihydrochloride
Procent renhet	98.0%
För användning med (applikation)	Cancer-Kinase/protease

CAS RN 1234015-54-3

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