CAS RN 1320288-17-2
IUPAC Namn:
N-(1-cyclohexylpiperidin-4-yl)-6-methoxy-7-[3-(piperidin-1-yl)propoxy]-2-[4-(propan-2-yl)-1,4-diazepan-1-yl]quinazolin-4-amine
Synonymer:
N-(1-cyclohexylpiperidin-4-yl)-2-(4-isopropyl-1,4-diazepan-1-yl)-6-methoxy-7-[3-(piperidin-1-yl)propoxy]quinazolin-4-amine
Molekylvikt (g/mol):
621.92
Molekylär sammansättning:
C36H59N7O2
InChi Key:
OUKWLRHRXOPODD-UHFFFAOYSA-N
SMILES:
COC1=CC2=C(NC3CCN(CC3)C3CCCCC3)N=C(N=C2C=C1OCCCN1CCCCC1)N1CCCN(CC1)C(C)C
1
–
3
av
3
Resultat
1
UNC0646, TRC
High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.
2
UNC0646, TRC
High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.
3
UNC0646, MedChemExpress
MedChemExpress UNC0646 is a potent and selective histone methyltransferase G9a inhibitor with an IC50 of 6 nM. UNC0646 is also a potent GLP inhibitor (IC50 G9a/GLP over SETD7, SUV39H2, SETD8 and PRMT3. UNC0646 reduces H3K9me2 levels in MDA-MB-231 cells with an IC50 of 26 nM.
