CAS RN 163769-88-8
IUPAC Namn:
16,17-dimethoxy-21,21-dimethyl-1,3,10-triazapentacyclo[11.8.0.0²,¹¹.0⁴,⁹.0¹⁴,¹⁹]henicosa-2,4,6,8,10,12,14(19),15,17-nonaene
Synonymer:
16,17-dimethoxy-21,21-dimethyl-1,3,10-triazapentacyclo[11.8.0.0²,¹¹.0⁴,⁹.0¹⁴,¹⁹]henicosa-2,4,6,8,10,12,14(19),15,17-nonaene
Molekylvikt (g/mol):
359.43
Molekylär sammansättning:
C22H21N3O2
InChi Key:
HIXSPVQXXDULHS-UHFFFAOYSA-N
SMILES:
COC1=CC2=C(C=C1OC)C1=CC3=NC4=CC=CC=C4N=C3N1C(C)(C)C2
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Resultat
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YM-90709, MedChemExpress
MedChemExpress YM-90709 is a novel IL-5 inhibitor which selectively blocks the binding of IL-5 to the IL-5 receptor (IL-5R).YM-90709 potently inhibits the binding of [125I]-IL-5 to IL-5R on human peripheral eosinophils and eosinophilic HL-60 clone 15 cells with IC50 values of 1.0 and 0.57 μM.
