CAS RN 1642303-38-5

IUPAC Namn: —

Synonymer: —

Molekylvikt (g/mol): —

Molekylär sammansättning: —

InChi Key: —

SMILES: —

MedChemExpress ITI-214 is a potent, CNS-active, orally bioavailable PDE1 inhibitor (Ki of 58 pM) with excellent selectivity against other PDE family members and against a panel of enzymes, receptors, transporters and ion channels. ITI-214 inhibits recombinant full-length human PDE1A, PDE1B and PDE1C with Kis of 33 pM, 380 pM and 35 pM, respectively. ITI-214 shows efficacy in various animal models of motor and cognitive functions.

Prissättning och tillgänglighet
Specifikationer

Molekylformel	C₂₉H₂₉FN₇O₅P
Rekommenderad förvaring	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Formel vikt	605.56
Hållbarhet	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Löslighetsinformation	DMSO : ≥ 30 mg/mL (49.54 mM)
Anteckningar om renhetsgrad	Research
Fysisk form	Solid
Kvalitet	Research
Färg	White
CAS	1642303-38-5
LEDER	O=C(C1=C(NC2=CC=CC=C2)N(CC3=CC=C(C4=NC(F)=CC=C4)C=C3)N=C1N56)N(C)C5=N[C@@]7([H])[C@]6([H])CCC7.O=P(O)(O)O
Molekylvikt (g/mol)	605.56
Kemiskt namn eller material	ITI-214
Procent renhet	99.54%
För användning med (applikation)	Neuroscience-Neuromodulation

CAS RN 1642303-38-5

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