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CAS RN 2040295-03-0

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Pexidartinib Hydrochloride Salt, TRC

High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.

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Pexidartinib Hydrochloride Salt, TRC

High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.

3

Pexidartinib hydrochloride, MedChemExpress

MedChemExpress Pexidartinib hydrochloride (PLX-3397 hydrochloride) is a potent, orally active, selective, and ATP-competitive colony stimulating factor 1 receptor (CSF1R or M-CSFR) and c-Kit inhibitor, with IC50s of 20 and 10 nM, respectively. Pexidartinib hydrochloride exhibits 10- to 100-fold selectivity for c-Kit and CSF1R over other related kinases. Pexidartinib hydrochloride induces cell apoptosis and has anti-cancer activity.

ENCOMPASS_PREFERRED
Molekylformel C20H16Cl2F3N5
Rekommenderad förvaring 4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Formel vikt 454.28
Hållbarhet 4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Löslighetsinformation DMSO : 60 mg/mL (132.08 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (ultrasonic) (insoluble)
Anteckningar om renhetsgrad Research
Fysisk form Solid
Kvalitet Research
Färg White
CAS 2040295-03-0
LEDER FC(C1=CC=C(CNC2=NC=C(CC3=CNC4=NC=C(Cl)C=C43)C=C2)C=N1)(F)F.Cl
Molekylvikt (g/mol) 454.28
Synonym PLX-3397 hydrochloride
Kemiskt namn eller material Pexidartinib hydrochloride
Procent renhet 99.67%
För användning med (applikation) Cancer-Kinase/protease