CAS RN 303162-79-0
IUPAC Namn:
N-{4-[2-ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl]pyridin-2-yl}benzamide
Synonymer:
N-{4-[2-ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl]pyridin-2-yl}benzamide
Molekylvikt (g/mol):
399.51
Molekylär sammansättning:
C24H21N3OS
InChi Key:
HEKAIDKUDLCBRU-UHFFFAOYSA-N
SMILES:
CCC1=NC(=C(S1)C1=CC(NC(=O)C2=CC=CC=C2)=NC=C1)C1=CC(C)=CC=C1
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Resultat
1
Tocris Bioscience™ TAK 715
CAS: 303162-79-0 Molekylformel: C24H21N3OS
2
TAK-715, MedChemExpress
MedChemExpress TAK-715 is an orally active and potent p38 MAPK inhibitor with IC50s of 7.1 nM, 200 nM for p38α and p38β, respectively. TAK-715 inhibits casein kinase I (CK1δ/ε) to regulate activation of Wnt/β-catenin signaling. TAK-715 shows good significant efficacy in a rat arthritis model.
