CAS RN 344897-95-6
IUPAC Namn:
4-{5-[(3-benzyl-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]furan-2-yl}benzoic acid
Synonymer:
4-{5-[(3-benzyl-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]furan-2-yl}benzoic acid
Molekylvikt (g/mol):
421.49
Molekylär sammansättning:
C22H15NO4S2
InChi Key:
AEZGRQSLKVNPCI-UHFFFAOYSA-N
SMILES:
OC(=O)C1=CC=C(C=C1)C1=CC=C(O1)C=C1SC(=S)N(CC2=CC=CC=C2)C1=O
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Resultat
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Leukadherin-1, MedChemExpress
MedChemExpress Leukadherin-1, a specific agonist of the leukocyte surface integrin CD11b/CD18, increases CD11b/CD18-dependent cell adhesion to fibrinogen with an EC50 of 4 μM. Leukadherin-1 enhances leukocyte adhesion to ligands (such as ICAM-1) and vascular endothelium and thus reduces leukocyte transendothelial migration and influx to the injury sites. Leukadherin-1 suppresses innate inflammatory signaling.
