CAS RN 868359-05-1
IUPAC Namn:
2-amino-3-{[4-(2-bromo-4,5-difluorophenoxy)phenyl]carbamoyl}propanoic acid
Synonymer:
2-amino-3-{[4-(2-bromo-4,5-difluorophenoxy)phenyl]carbamoyl}propanoic acid
Molekylvikt (g/mol):
415.19
Molekylär sammansättning:
C16H13BrF2N2O4
InChi Key:
BNYDDAAZMBUFRG-UHFFFAOYNA-N
SMILES:
NC(CC(=O)NC1=CC=C(OC2=CC(F)=C(F)C=C2Br)C=C1)C(O)=O
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2
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Resultat
1
Tocris Bioscience™ WAY 213613
CAS: 868359-05-1 Molekylformel: C16H13BrF2N2O4
2
WAY-213613, MedChemExpress
MedChemExpress WAY-213613 is a potent, selective nonsubstrate reuptake inhibitor of GLT-1/EAAT2 with IC50 of 85 nM EAAT2. It displays 59- and 44-fold selectivity over EAAT1 and EAAT3 (IC50s are 5 and 3.8 μM, respectively). WAY-213613 shows no activity at ionotropic and metabotropic glutamate receptors. It is a potential tool for the elucidation of EAAT2 function.
