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Thermo Scientific Chemicals 2',3'-Dideoxycytidine, 98+%
CAS: 7481-89-2 | C9H13N3O3 | 211.22 g/mol
1205.00 SEK - 4145.00 SEK
Chemical Identifiers
CAS | 7481-89-2 |
---|---|
Molecular Formula | C9H13N3O3 |
Molecular Weight (g/mol) | 211.22 |
MDL Number | MFCD00012188 |
InChI Key | WREGKURFCTUGRC-KGQMAECUNA-N |
Synonym | zalcitabine, 2',3'-dideoxycytidine, dideoxycytidine, ddcyd, hivid, ddc, cytidine, 2',3'-dideoxy, zalcitibine, ddc antiviral, 4-amino-1-2r,5s-5-hydroxymethyl tetrahydrofuran-2-yl pyrimidin-2 1h-one |
PubChem CID | 24066 |
ChEBI | CHEBI:10101 |
SMILES | NC1=NC(=O)N(C=C1)[C@H]1CC[C@@H](CO)O1 |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
11322906
|
Thermo Scientific Chemicals
L10619.MF |
50 mg |
1205.00 SEK
50mg |
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11332906
|
Thermo Scientific Chemicals
L10619.MD |
250 mg |
4145.00 SEK
250mg |
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Description
2',3'-Dideoxycytidine in cells, it is phosphorylated to the active triphosphate form, ddCTP, which acts as a substrate for HIV reverse transcriptase (Ki = 51 nM). It incorporates into viral DNA where it terminates chain elongation when the missing hydroxyl group is encountered. It is also is used as a DNA chain-terminating nucleotide for DNA sequencing methods based on the Sanger chain-termination method.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Chemical Identifiers
7481-89-2 | |
211.22 | |
WREGKURFCTUGRC-KGQMAECUNA-N | |
24066 | |
NC1=NC(=O)N(C=C1)[C@H]1CC[C@@H](CO)O1 |
C9H13N3O3 | |
MFCD00012188 | |
zalcitabine, 2',3'-dideoxycytidine, dideoxycytidine, ddcyd, hivid, ddc, cytidine, 2',3'-dideoxy, zalcitibine, ddc antiviral, 4-amino-1-2r,5s-5-hydroxymethyl tetrahydrofuran-2-yl pyrimidin-2 1h-one | |
CHEBI:10101 |
Specifications
7481-89-2 | |
Glass bottle | |
MFCD00012188 | |
zalcitabine, 2',3'-dideoxycytidine, dideoxycytidine, ddcyd, hivid, ddc, cytidine, 2',3'-dideoxy, zalcitibine, ddc antiviral, 4-amino-1-2r,5s-5-hydroxymethyl tetrahydrofuran-2-yl pyrimidin-2 1h-one | |
WREGKURFCTUGRC-KGQMAECUNA-N | |
4-amino-1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one | |
24066 | |
211.22 | |
Solid |
216°C to 220°C | |
C9H13N3O3 | |
654956 | |
Soluble in water (76.4mg/ml at 25°C),DMSO (42mg/ml at 25°C),and ethanol (<1mg/ml at 25°C). | |
NC1=NC(=O)N(C=C1)[C@H]1CC[C@@H](CO)O1 | |
211.22 | |
CHEBI:10101 | |
≥98% | |
2′,3′-Dideoxycytidine |
Safety and Handling
P201-P202-P281-P308+P313-P501c
H351
missing translation for 'rtecsNumber' : HA3870000
missing translation for 'tsca' : No
Recommended Storage : Keep cold
- 2',3'-Dideoxycytidine
Signal Word
- Warning
Hazard Category
- Carcinogenicity Category 2
Hazard Statement
- H351-Suspected of causing cancer.
Precautionary Statement
- P201-Obtain special instructions before use.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P308+P313-IF exposed or concerned: Get medical advice/attention.
Supplemental information
- MIXTURE LIST-Contains : 2,3-Dideoxycytidine
RUO – Research Use Only
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