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  6. Thermo Scientific Chemicals 2'-Deoxyguanosine hydrate, 99%

Thermo Scientific Chemicals 2'-Deoxyguanosine hydrate, 99%

Produktkod. 11343566
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Produktkod. 11343566

Brand: Thermo Scientific Chemicals L14519.MC

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Beskrivning

CAS: 961-07-9 | C10H13N5O4 | 267.25 g/mol

Deoxyguanosine (dG) is a purine nucleoside that upon sequential phosphoylation (kinases) forms dGTP which is used by DNA polymerases and reverse transcriptases to synthesis DNA(s). Deoxyguanosine is the most electron rich of the four canonical bases and includes many nucleophilic sites which are susceptible to oxidative damage. This makes deoxyguanosine and its oxidized derivatives useful reagents to study mechanisms of oxidative damage to nucleosides and nucleotides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Deoxyguanosine (dG) is a purine nucleoside that upon sequential phosphoylation (kinases) forms dGTP which is used by DNA polymerases and reverse transcriptases to synthesis DNA(s). Deoxyguanosine is the most electron rich of the four canonical bases and includes many nucleophilic sites which are susceptible to oxidative damage. This makes deoxyguanosine and its oxidized derivatives useful reagents to study mechanisms of oxidative damage to nucleosides and nucleotides.

Solubility
Slightly soluble in water.

Notes
Store in cool. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.
TRUSTED_SUSTAINABILITY

Kemiska identifierare

CAS 961-07-9
Molekylformel C10H13N5O4
Molekylvikt (g/mol) 267.25
MDL-nummer MFCD00150760
InChI-nyckel YKBGVTZYEHREMT-DWFKHXNSNA-N
Synonym 2'-deoxyguanosine, deoxyguanosine, guanine deoxyriboside, 2-deoxyguanosine, guanosine, 2'-deoxy, guanine deoxy nucleoside, 2'-deoxy-guanosine, 2;-deoxyguanosine, unii-g9481n71ro, guanine, 9-2-deoxy-beta-d-erythro-pentofuranosyl
PubChem CID 187790
ChEBI CHEBI:17172
IUPAC-namn 2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one
LEDER NC1=NC2=C(N=CN2[C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)N1

Specifikationer

Kemiskt namn eller material 2'-Deoxyguanosine hydrate
Kvantitet 100 mg
Beilstein 39814
Löslighetsinformation Slightly soluble in water.
Optisk rotation −32° (c=0.5 in Water)
Formel vikt 267.25 (Anhydrous)
Procent renhet 99%

Säkerhet och hantering

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  • Akut toxicitet Kategorija 4
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  • H302-Skadligt vid förtäring.
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  • P301+P330+P331-VID FÖRTÄRING: Skölj munnen. Framkalla INTE kräkning.
  • P312-Vid obehag, kontakta GIFTINFORMATIONSCENTRALEN/läkare/ .

RUO – Research Use Only

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