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Tocris Bioscience™ 2R,6R-Hydroxynorketamine hydrochloride
Beskrivning
2R,6R-Hydroxynorketamine hydrochloride is a ketamine metabolite. It enhances AMPA receptor-mediated excitatory post-synaptic potentials in the CA1 region of hippocampal slices and decreases intracellular DL>D-serine (a NMDA co-agonist) concentrations in PC-12 cells (IC50 = 0.68 nM). 2R,6R-Hydroxynorketamine upregulates KCNQ2 channels in mouse ventral hippocampal glutamatergic neurons in vitro and in vivo. Exerts antidepressant effects in mice. Lacks ketamine-related side effects. 2S,6S-Enantiomer and Racemate also available.
Specifikationer
Specifikationer
| Kemiskt namn eller material | (2R,6R)-2-Amino-2-(2-chlorophenyl)-6-hydroxycyclohexanone hydrochloride |
| CAS | 1430202-69-9 |
| Kvantitet | 10 mg |
| Mål | AMPA Receptor Agonists |
| Molekylformel | C12H14ClNO2.HCl |
| Renhet | 98% |
Produkttitel
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