4-Thiouridine, 98+% Alfa Aesar™
Brand: Alfa Aesar J60679.MC
UNSPSC : 12352208
Additional Details : CAS Number : 13957-31-8 Weight : 0.00010kg
4-Thiouridine is a constituent of several transfer RNA′s. 4-Thiouridine is a thionucleobase used as an antisense agent. Widely used for RNA analysis including RNA-RNA cross coupling and RNA labelling. 4-Thiouridine is a photoreactive (crosslinking) uridine analogue that upon phosphorylation to 4-thioUTP may be incorporated into RNA structures. 4-Thiouridine may be used to study the specificity and kinetics of uridine-cytidine kinases. 4-Thio Uridine is typically used to modify oligos slated for RNA, or RNA-protein, structural studies. A 4-thio-rU modified RNA pentamer was used to study the effect of this modification on codon-anticodon interaction when it is in the wobble position of tRNA.
Soluble in water (20 mg/ml), and methanol (10 mg/ml).
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, heat.