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4EBP1 Mouse anti-Human, Mouse, Rat, Clone: 2C3F3, Proteintech

Mouse Monoclonal Antibody

1656.73 SEK - 4721.67 SEK

Specifications

Antigen 4EBP1
Clone 2C3F3
Concentration 1.6 mg/mL
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16827285
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Proteintech
60246-1-IG-20UL
20 μL
1656.73 SEK
20µL
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Estimated Shipment: 03-04-2024
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16817285
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Proteintech
60246-1-IG-150UL
150 μL
4721.67 SEK
150µL
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Estimated Shipment: 03-04-2024
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Description

Description

The kinesins constitute a large family of microtubule-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell. Individual kinesin members play crucial roles in cell division, intracellular transport, and membrane trafficking events including endocytosis and transcytosis. KIF1C is a member of the KIF1/Unc104 family of kinesin-like proteins, which are involved in the transport of mitochondria or synaptic vesicles in axons. Human KIF1C maps to chromosome 17p13 and encodes a predicted 1,103 amino acid protein with abundant expression in heart and skeletal muscle. Tyrosine phosphorylation is a putative regulator of KIF1C mediated retrograde transport of Golgi vesicles to the endoplasmic reticulum. KIF1C is capable of forming homodimers and can noncovalently associate with 14-3-3 beta, gamma, epsilon and zeta. In mouse macrophages, KIF1C is required for anthrax lethal toxin resistance.
Specifications

Specifications

4EBP1
1.6 mg/mL
Monoclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
4E BP1, 4EBP1, BP 1, eIF4E binding protein 1, EIF4EBP1, PHAS I
EIF4EBP1
IgG2b
Protein A
Antibody
2C3F3
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
Mouse
Human, Mouse, Rat
Q13541, Q60876, Q62622
116636, 13685, 1978
4EBP1 Fusion Protein Ag18985
Primary
-20°C
EIF4EBP1
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