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Invitrogen™ ABCB7 Polyclonal Antibody

Beskrivning
Antibody detects endogenous levels of total ABCB7.
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been implicated in X-linked sideroblastic anemia with ataxia.
Specifikationer
Specifikationer
| Antigen | ABCB7 |
| Användningsområden | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Klassificering | Polyclonal |
| Koncentration | 1 mg/mL |
| Konjugera | Unconjugated |
| Formulering | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gen | ABCB7 |
| Genaccessionsnr. | O75027, Q61102 |
| Gene Alias | AA517758; ABC transporter 7 protein; ABC7; ABCB7; ASAT; Atm1p; ATP binding cassette subfamily B member 7; ATP-binding cassette 7; ATP-binding cassette sub-family B member 7; ATP-binding cassette sub-family B member 7, mitochondrial; ATP-binding cassette sub-family B member 7, mitochondrial-like protein; ATP-binding cassette transporter 7; ATP-binding cassette, subfamily B (MDR/TAP), member 7; ATP-binding cassette, sub-family B (MDR/TAP), member 7; ATP-binding cassette, sub-family B, member 7; ATP-binding cassette, sub-family B, member 7, mitochondrial; AU019072; EST140535; fc20c02; wu:fc20c02 |
| Gensymboler | ABCB7 |
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Produkttitel
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