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Invitrogen™ ABCB7 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA583254
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Beskrivning
Immunogen sequence: GAMKDVVKHR TSIFIAHRLS TVVDADEIIV LDQGKVAERG THHGLLANPH SIYSEMWHTQ SSRVQNHDNP KWEAKKENIS KEEERKKLQE EI Highest antigen sequence indentity to the following orthologs: Mouse - 86%, Rat - 87%.
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been implicated in X-linked sideroblastic anemia with ataxia.
Specifikationer
| ABCB7 | |
| Polyclonal | |
| Unconjugated | |
| ABCB7 | |
| AA517758; ABC transporter 7 protein; ABC7; ABCB7; ASAT; Atm1p; ATP binding cassette subfamily B member 7; ATP-binding cassette 7; ATP-binding cassette sub-family B member 7; ATP-binding cassette sub-family B member 7, mitochondrial; ATP-binding cassette sub-family B member 7, mitochondrial-like protein; ATP-binding cassette transporter 7; ATP-binding cassette, subfamily B (MDR/TAP), member 7; ATP-binding cassette, sub-family B (MDR/TAP), member 7; ATP-binding cassette, sub-family B, member 7; ATP-binding cassette, sub-family B, member 7, mitochondrial; AU019072; EST140535; fc20c02; wu:fc20c02 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 22 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Immunocytochemistry | |
| 0.6 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| O75027 | |
| ABCB7 | |
| Recombinant protein corresponding to Human ABCB7. Recombinant protein control fragment (Product #RP-95445). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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