ACT1 Rat anti-Human, Clone: 9ACT12, eBioscience™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 14-4040-82
Additional Details : Weight : 0.01000kg
DescriptionThis gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Two alternative transcripts encoding different proteins have been identified. A third transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene.
|PBS with 0.09% sodium azide; pH 7.2|
|RP3-487J7.3, ACT1, C6orf2, C6orf4, C6orf5, C6orf6, CIKS, PSORS13; NFkB-activating protein ACT1; TRAF3-interacting protein 2; adapter protein CIKS; connection to IKK and SAPK/JNK; nuclear factor NF-kappa-B activator 1|
For Research Use Only.