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Thermo Scientific™ ActivX™ TAMRA-FP Serine Hydrolase Probe

ActivX™ probes have been designed to selectively label and enrich serine hydrolases through binding of their respective active sites with tagged fluorophosphonate to enable assessment of enzyme activity.

Brand:  Thermo Scientific™ 88318

4512.50 SEK valid until 2024-03-29
Use promo code "21653" to get your promotional price.



Additional Details : Weight : 1.36080kg

Product Code. 11854624

  • 4750.00 SEK / Each
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Description

Description

The TAMRA-FP probe feature a reactive fluorophosphonate group that is used to label and detect active serine hydrolases by fluorescent gel imaging, capillary electrophoresis or mass spectrometry. An anti-TAMRA antibody is also available for immuno-enrichment of TAMRA-FP probe-labeled proteins.

ActivX™ active-site enrichment probes are advantageous for determining active enzyme levels through the use of analog-tagged probes to allow profiling of both inactive and active enzymes. The ActivX probes selectively enrich only those enzymes that are functionally active and biologically relevant at the time of labeling. With selective enrichment, one can identify and profile target enzyme classes across samples or can assess the specificity and affinity of enzyme inhibitors.

The serine hydrolase superfamily is one of the largest, most diverse enzyme families in eukaryotic proteomes. Serine hydrolases are generally grouped into two large families: serine proteases (e.g., trypsin, elastase and thrombin) and metabolic serine hydrolases. Metabolic serine hydrolases are divided into multiple enzyme subclasses (e.g., esterases, lipases, amidases and peptidases) based on structure, catalytic mechanism and substrate preference. These probes can be used to assess activity or screen small molecule inhibitors against enzymes derived from cell lysates, subcellular fractions, tissues and recombinant proteins.

These products are subject to a limited use label license.

Specifications

Specifications

ActivX™ TAMRA-FP Serine Hydrolase Probe
Store at -80°C away from light. Stock solutions in DMSO can be stored at -20°C for 6 months.
Chemiluminescence, Mass Spectrometry, Western Blot
ActivX™
Pull-Down
Fluorophosphonate (FP) probe
Tube, Spin Column
TAMRA-fluorophosphonate, MW 680
Protein Quantitation Assay
Serine Hydrolase Substrate
6.8 μg
Serine Hydrolase
Other Label(s) or Dye(s)
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For Research Use Only. Not for use in diagnostic procedures.