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AKT1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 55230-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16826725

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Description

Description

This antibody is specific to AKT1. It has no cross reaction to AKT2 and AKT3.

The Akt family of serine/threonine protein kinases (also called protein kinase B/PKB) plays a key role in insulin signaling, cellular survival, and transformation. Akt1 is activated by phosphorylation on residues threonine 308 and Serine 473. Thr308, in the catalytic domain, is phosphorylated by the protein kinase PDK1, and Ser473, in the COOH-terminal regulatory domain, is phosphorylated by putative serine 473 kinase. To date, a couple of proteins have been shown to physically interact with PKB.
Specifications

Specifications

AKT1
Polyclonal
Unconjugated
AKT1
AKT, AKT1, PKB, PKB ALPHA, PRKBA, Protein kinase B, Proto oncogene c Akt, RAC, RAC ALPHA, RAC PK alpha
Rabbit
Antigen Affinity Chromatography
RUO
11651, 207
-20°C
Liquid
Western Blot, Immunohistochemistry (Paraffin)
0.31 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P31749, P31750
AKT1
Peptide
20 μL
Primary
Mouse, Human
Antibody
IgG
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