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Invitrogen™ alpha Synuclein Monoclonal Antibody (Syn 211)
GREENER_CHOICE

Mouse Monoclonal Antibody

Brand:  Invitrogen™ AHB0261

Produktkod. 10160093

  • 4430.00 SEK / 100µg

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For Research Use Only. All usage must comply with product instructions.

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Beskrivning

Beskrivning

A suggested positive control for this product is SHSY-5Y cells. It will not cross-react with mouse or rat.

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. These proteins are abundant in the brain and play a role in regulating synaptic transmission and membrane trafficking. Alpha- and beta-synuclein have been shown to selectively inhibit phospholipase D2, suggesting that they may also be involved in signaling pathways. Defects in the SNCA gene, which encodes alpha-synuclein, have been implicated in the pathogenesis of Parkinson's disease. Additionally, alpha-synuclein peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Multiple alternatively spliced transcripts encoding different isoforms have been identified for this gene. Diseases associated with SNCA include Parkinson Disease 1, Autosomal Dominant and Dementia, Lewy Body.
TRUSTED_SUSTAINABILITY
Specifikationer

Specifikationer

alpha Synuclein
Monoclonal
0.5 mg/mL
PBS with 0.1% BSA and 0.1% sodium azide; pH 7.2
P37840
SNCA
Recombinant human alpha-synuclein.
100 μg
Primary
Human
Antibody
IgG1
ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Syn 211
Unconjugated
SNCA
Alpha synuclein; alphaSYN; alpha-synuclein; NACP; non A-beta component of AD amyloid; non-A beta component of AD amyloid; non-A4 component of amyloid; Non-A4 component of amyloid precursor; PARK1; PARK4; PD1; Snca; Syn; synuclein alpha; synuclein alpha-140; synuclein, alpha; synuclein, alpha (non A4 component of amyloid precursor)
Mouse
Protein A/G
RUO
6622
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Liquid
Responsibly packaged
Produktförslag

Produktförslag

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