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Amlodipine besylate, 98+%, Thermo Scientific™
An L-type calcium channel antagonist with potent antioxidant activity
Brand: Thermo Scientific Alfa Aesar J62164.06
| Kvantitet | 5g |
|---|
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Beskrivning
This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.
ApplicationsAmlodipine besylate is used as a dihydropyridine calcium channel blocker. It is also used as an antianginal and antihypertensive. Amlodipine besylate also displays vasoprotective effects in cardiovascular disease and inhibits Ca2+-induced contractions in depolarized rat aorta (IC50 = 1.9 nM). Amlodipine besylate has been shown to inhibit proliferation of human vascular smooth muscle cells and epidermoid carcinoma A431 cells.
Solubility
Soluble in DMSO (≥20 mg/mL), water (10 mM), chloroform, ethanol (≥14 mg/mL), and methanol.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from strong oxidizing agents.
Kemiska identifierare
| 111470-99-6 | |
| 567.05 | |
| ZPBWCRDSRKPIDG-UHFFFAOYSA-N | |
| 60496 | |
| benzenesulfonic acid;3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate |
| C26H31ClN2O8S | |
| MFCD00887594 | |
| amlodipine besylate, amlodipine besilate, cardiorex, amlodipine benzenesulfonate, istin, amdepin, amdipin, amlodin, amlogard, amlopin | |
| CHEBI:2669 | |
| CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN.C1=CC=C(C=C1)S(=O)(=O)O |
Specifikationer
| Amlodipine besylate | |
| C26H31ClN2O8S | |
| 5g | |
| amlodipine besylate, amlodipine besilate, cardiorex, amlodipine benzenesulfonate, istin, amdepin, amdipin, amlodin, amlogard, amlopin | |
| ZPBWCRDSRKPIDG-UHFFFAOYSA-N | |
| benzenesulfonic acid;3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate | |
| 60496 | |
| 567.05 |
| 111470-99-6 | |
| MFCD00887594 | |
| 14,491 | |
| Soluble in DMSO (?20mg/mL),water (10 mM),chloroform,ethanol (?14mg/mL),and methanol. | |
| CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN.C1=CC=C(C=C1)S(=O)(=O)O | |
| 567.05 | |
| CHEBI:2669 | |
| ≥98% |
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