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  7. Amlodipine besylate, 98+%

Amlodipine besylate, 98+%

Produktkod. 15464589
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Produktkod. 15464589 Leverantör Thermo Scientific Alfa Aesar Leverantörsnummer J62164.06
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Beskrivning

An L-type calcium channel antagonist with potent antioxidant activity | CAS: 111470-99-6 | C26H31ClN2O8S | 567.05 g/mol

Amlodipine besylate is used as a dihydropyridine calcium channel blocker. It is also used as an antianginal and antihypertensive. Amlodipine besylate also displays vasoprotective effects in cardiovascular disease and inhibits Ca2+-induced contractions in depolarized rat aorta (IC50 = 1.9 nM). Amlodipine besylate has been shown to inhibit proliferation of human vascular smooth muscle cells and epidermoid carcinoma A431 cells.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Amlodipine besylate is used as a dihydropyridine calcium channel blocker. It is also used as an antianginal and antihypertensive. Amlodipine besylate also displays vasoprotective effects in cardiovascular disease and inhibits Ca2+-induced contractions in depolarized rat aorta (IC50 = 1.9 nM). Amlodipine besylate has been shown to inhibit proliferation of human vascular smooth muscle cells and epidermoid carcinoma A431 cells.

Solubility
Soluble in DMSO (≥20 mg/mL), water (10 mM), chloroform, ethanol (≥14 mg/mL), and methanol.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Kemiska identifierare

CAS 111470-99-6
Molekylformel C26H31ClN2O8S
Molekylvikt (g/mol) 567.05
MDL-nummer MFCD00887594
InChI-nyckel ZPBWCRDSRKPIDG-UHFFFAOYSA-N
Synonym amlodipine besylate, amlodipine besilate, cardiorex, amlodipine benzenesulfonate, istin, amdepin, amdipin, amlodin, amlogard, amlopin
PubChem CID 60496
ChEBI CHEBI:2669
IUPAC-namn benzenesulfonic acid;3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
LEDER CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN.C1=CC=C(C=C1)S(=O)(=O)O

Specifikationer

Kemiskt namn eller material Amlodipine besylate
Smältpunkt 195°C to 204°C
Färg White
Kvantitet 5 g
Merck Index 14,491
Löslighetsinformation Soluble in DMSO (?20mg/mL),water (10 mM),chloroform,ethanol (?14mg/mL),and methanol.
Formel vikt 567.05
Procent renhet ≥98%
Fysisk form Solid

RUO – Research Use Only

Produkttitel
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