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Ampicillin sodium salt

Produktkod. 15465979
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Produktkod. 15465979 Leverantör Thermo Scientific Alfa Aesar Leverantörsnummer J63807.06
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Beskrivning

Ampicillin sodium salt, CAS # 69-52-3, is the sodium salt form of ampicillin, a semisynthetic derivative of aminopenicillin compound that shows antibacterial activity against both gram-positive and gram-negative bacteria. | CAS: 69-52-3 | C16H21N3NaO4S | 374.411 g/mol

Ampicillin sodium salt is a reagent for transformed cells expressing beta-lactamase. It acts as a structural analogue of acyl-D-alanyl-D-alanine, acylates the transpeptidase enzyme and prevents the cross-linking of the peptidoglycan of the cell wall necessary for the growth of the bacterium.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Ampicillin sodium salt is a semi-synthetic derivative of penicillin with a broad-spectrum antibacterial activity against several species, including Bacillus subtilis, Staphylococcus aureus, Escherichia coli, and Ralstonia solanacearum

• It can inhibit bacterial cell wall synthesis by binding to penicillin-binding proteins, inhibiting peptidoglycan synthesis, which is an essential component of the bacterial cell wall

Application

• Ampicillin sodium salt has been used as a reagent for transformed cells that express β-lactamase

• It can be used to select for ampicillin resistance in mutated and transformed cells

• Ampicillin sodium salt acts as a structural analog of acyl-D-alanyl-D-alanine, acylates the transpeptidase enzyme preventing the cross-linking of the cell wall peptidoglycan, which is necessary for the growth of the bacterium

TRUSTED_SUSTAINABILITY

Kemiska identifierare

CAS 69-52-3
Molekylformel C16H21N3NaO4S
Molekylvikt (g/mol) 374.411
MDL-nummer MFCD00064313
InChI-nyckel BSFVNXCYXDYHOD-ZQDFAFASSA-N
PubChem CID 131673879
IUPAC-namn (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;molecular hydrogen;sodium
LEDER [HH].CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)N)C(=O)O)C.[Na]

Specifikationer

Kemiskt namn eller material Ampicillin sodium salt
Typ Ampicillin Sodium Salt
Fysisk form Powder
Smältpunkt 215°C
Färg White
Kvantitet 5 g
Beilstein 4119211
Merck Index 14,586
Löslighetsinformation Freely soluble in water; Sparingly soluble in acetone
Formel vikt 371.39

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  • Ampicillin sodium salt
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  • Luftvägssensibilisering Kategorija 1
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  • H317-Kan orsaka allergisk hudreaktion.
  • H334-Kan orsaka allergi- eller astmasymtom eller andningssvårigheter vid inandning.
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  • P280-Använd skyddshandskar/skyddskläder/ögonskydd/ansiktsskydd.
  • P284-[Vid otillräcklig ventilation], använd andningsskydd.
  • P302+P352-VID HUDKONTAKT: Tvätta med mycket vatten/.
  • P304+P340-VID INANDNING: Flytta personen till frisk luft och se till att andningen underlättas.
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  • P342+P311-Vid besvär i luftvägarna: Kontakta GIFTINFORMATIONSCENTRALEN/läkare/ .
 Supplerende oplysninger
  • MIXTURE LIST-Contain: Ampicillin sodium salt

RUO – Research Use Only

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