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Invitrogen™ AMPK (A1/B1/G3) Recombinant Human Protein

AMPK (A1/B1/G3) is a heterotrimeric protein consisting of an α catalytic subunit, and non-catalytic β and γ subunits. Recombinant full-length human AMPK (combination of A1/B1/G3 subunits) was expressed by baculovirus in Sf9 insect cells using a C-terminal His tags.

Brand:  Invitrogen™ PV6241

Additional Details : Weight : 0.01000kg

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Product Code. 15448903

  • 2975.00 SEK / 10µg


Estimated Shipment date
from Supplier 04-01-2018
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Description

Description

AMPKs are an important energy-sensing enzyme group in the cells that monitor energy status particularly in response to stress. AMPKs regulate fatty acid and cholesterol synthesis by regulating the key rate-limiting enzymes acetyl-CoA carboxylase and hydroxy beta-methylglutaryl-CoA reductase. The gamma subunit is dominantly expressed in skeletal muscle where it may play a key role in the regulation of energy metabolism.

  • Validated in LanthaScreen™ Kinase Binding Assay
  • Protocols available for simple use and optimized performance
  • Multiple pack sizes available for convenient use
Specifications

Specifications

Target & Lead Identification & Validation|Kinase Biology|Kinase Proteins & Expression Reagents|Protein Biology|Enzyme & Protein Activity Assays|Kinase Activity|Protein Assays and Analysis|Industrial & Applied Science|Pharma & Biopharma
63.6 /31.2/ 55.1kDa
Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws.
Kinase Assay
Human
His Tag
50mM sodium phosphate pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.2mM DTT, 25% glycerol
10μg
Subunit A1: PRKAA1, MGC33776, MGC57364 Subunit B1: PRKAB1, AMPK, HAMPKb, MGC17785 Subunit G3: PRKAG3
aa 10-end
Yes
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