Invitrogen™ AMPK A2/B1/G1 Recombinant Human Protein
AMP-activated protein kinase (AMPK) is a heterotrimeric complex that acts as a sensor of cellular energy levels. Activation of AMPK is of interest for the treatment of type 2 diabetes.
Brand: Invitrogen™ PR8694C
Additional Details : Weight : 0.01000kg
The signaling cascades initiated by activating AMPK are critical to regulating metabolic events in the liver, skeletal muscle, heart, adipose tissue, and pancreas. An impairment in fuel metabolism that occurs in obesity is a factor leading to Type 2 diabetes. The insulin resistance associated with type 2 diabetes is most profound at the level of skeletal muscle, the primary site of glucose and fatty acid utilization.
|NP_0062243.2 I NP_006244.2 I NP_002724.1|
|Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.|
|CAMKL Kinase Family|
|Protein Biology|Enzyme & Protein Activity Assays|Kinase Activity|Protein Assays and Analysis|
|50mM Tris, pH 7.5, 150mM NaCl, 0.02% Triton X-100, 0.5mM EDTA, 2mM DTT, 50% Glycerol|
|RUO - research use only|
|GST Tag, His Tag|