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AMPK beta 1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 10308-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16876603

  • 3313.85 SEK / 150µL
Estimated Shipment: 07-12-2021

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Description

Description

AMPK beta 1 is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.
Specifications

Specifications

AMPK beta 1
0.23 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q9R078, Q9Y478
AMPK, AMPK beta 1, AMPK subunit beta 1, AMPKb, HAMPKb, PRKAB1
Rabbit
IgG
150 μL
-20°C
Primary
19079, 5564
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
PRKAB1
Liquid
Prkab1
AMPK beta 1 Fusion Protein Ag0301
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
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Special Offers

Special Offers