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BACE2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA519950

Additional Details : Weight : 0.01000kg

Product Code. 12838162

  • 3245.00 SEK / 100µg


Estimated Shipment date
from Supplier 07-02-2020
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Description

Description

BACE2 or Beta Secretase 2 is responsible for the proteolytic processing of the amyloid precursor protein (APP). BACE2 cleaves APP between residues 690 and 691. This cleavage leads to the generation and extracellular release of beta-cleaved soluble APP. BACE2 is also know to cleave APP between residues 671 and 672. Accumulation of APP is a signature of Alzheimer disease and frequent complication of adult Down syndrome patients.
Specifications

Specifications

BACE2
Polyclonal
PBS with 0.02% sodium azide
Q9Y5Z0, Q9JL18, Q6IE75
BACE2
A synthetic peptide corresponding to amino acids 44 to 59 of human BACE2.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunohistochemistry, Western Blot
Unconjugated
BACE2
Liquid
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
25825, 288227, 56175
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