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CD43 (Ly-48, Leukosialin) Rat anti-Mouse, APC, Clone: S7, BD
Rat Monoclonal Antibody
Brand: BD Biosciences 560663
Beskrivning
The S7 monoclonal antibody specifically binds to the 115 kDa glycosylated form of CD43 (Ly-48, Leukosialin). CD43 is expressed on IL-7-responsive pro-B cells, plasma cells, peritoneal and splenic CD5+ B cells (B-1 cells), granulocytes, monocytes, macrophages, platelets, natural killer cells, thymocytes, peripheral T cytotoxic/suppressor cells, and most T helper cells, but not resting conventional peripheral B cells. CD43 expression has also been detected on pluripotent hematopoietic stem cells and myeloid, lymphoid, and NK-cell progenitors in the bone marrow. Studies of CD43-deficient mice indicate that CD43 participates in the negative regulation of T-cell activation and adhesion.
Specifikationer
| CD43 | |
| Monoclonal | |
| 0.2mg/mL | |
| Spn ; Sialophorin; Leukosialin; Ly-48; Ly48; Galgp; LEUK | |
| Rat | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| Flow Cytometry | |
| S7 | |
| APC | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| Mouse plasmacytoma MOPC-315 | |
| 50 μg | |
| Immunology | |
| Mouse | |
| IgG2a κ |
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