missing translation for 'onlineSavingsMsg'
Learn More

CD5 Rat anti-Mouse, PE, Clone: 53-7.3, BD

Rat Monoclonal Antibody

2740.00 SEK - 5175.00 SEK

Specifications

Antigen CD5
Clone 53-7.3
Concentration 0.2mg/mL
Applications Flow Cytometry
Classification Monoclonal
View More Specs

Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
10095394
View Documents Promotion Details
BD Biosciences
553022
0.1 mg
2740.00 SEK
Each
View alternative products
Save Up to 
»
Estimated Shipment: 26-04-2024
to see stock.
Please to purchase this item. Need a web account? Register with us today!
15836938
View Documents Promotion Details
BD Biosciences
553023
0.2 mg
5175.00 SEK
Each
View alternative products
Save Up to 
»
Estimated Shipment: 26-04-2024
to see stock.
Please to purchase this item. Need a web account? Register with us today!
Description

Description

The 53-7.3 clone has been reported to react with a monomorphic epitope of CD5, a member of the scavenger receptor cysteine-rich protein superfamily and the major ligand of CD72, found on thymocytes, T lymphocytes, thymic NK-T cells, and a subset of B lymphocytes, but not on NK cells or splenic NK-T cells. The level of surface CD5 expression is developmentally regulated in the thymus, starting with low levels on CD4-CD8- thymocytes and increasing as they mature to CD4+CD8+ then CD4+CD8- or CD4-CD8+ thymocytes. Relatively high levels are maintained on peripheral T lymphocytes. The level of CD5 antigen detected on T helper cells has been reported to be somewhat higher than that on T cytotoxic/suppressor and B cells. Few, if any, intestinal intraepithelial lymphocytes bearing the γδ T-cell receptor express CD5. Phenotypic, anatomical, functional, developmental, and pathogenic characteristics of peripheral CD5+ B cells suggest that they may represent a distinct lineage, known as B-1 cells. The frequency of these CD5+ B cells has been reported to show strain-dependent variation. An additional population of CD5+ B lymphocytes resides in the thymus, where it matures from intrathymic B-cell progenitors. It has been proposed that CD5 is a costimulatory molecule which mediates interactions of cells in the immune system and negatively regulates signal transduction mediated by the T-cell receptor and B-cell receptor. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Host Species: Rat
Clone: 53-7.3
Isotype: IgG2a κ
Species Reactivity: Mouse
Immunogen: Mouse Thymus / Spleen

Flow Cytometry

Specifications

Specifications

CD5
0.2mg/mL
Monoclonal
Rat
Immunology
Aqueous buffered solution containing ≤0.09% sodium azide.
IgG2a κ
Affinity Purified
Lymphocyte antigen 1; Cd5; Ly-12; Ly-A; Lyt-1
53-7.3
Flow Cytometry
PE
RUO
Mouse
Mouse Thymus / Spleen
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Videos
SDS
Documents

Documents

Product Certifications

For Research Use Only.