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CD71 Mouse anti-Human, Unlabeled, Clone: M-A712, BD

Product Code. 15838248
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Kvantitet:
0.1 mg
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15838248 0.1 mg
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Product Code. 15838248 missing translation for 'mfr' BD Biosciences missing translation for 'supplierNo' 555534
 Begränsad artikel
Beräknad leverans: 15-09-2026
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Description

Mouse Monoclonal Antibody

The M-A712 monoclonal antibody specifically binds to CD71 which is also known as the transferrin receptor (TFR). This type II transmembrane glycoprotein is expressed on cells as a disulfide-linked homodimer comprised of 95 kDa monomers. CD71 is expressed on activated lymphocytes, monocytes, macrophages, erythroid progenitors, brain endothelium, and most proliferating cells. CD71 is not expressed on resting lymphocytes and is upregulated during lymphocyte responses to antigens or mitogens. Through an endocytic pathway, the transferrin receptor mediates cellular iron uptake by binding and internalizing iron that is bound to transferrin. After releasing iron within the low pH endosomal environment, transferrin and its receptor can be recycled to the cell surface.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD71
Användningsområden Flow Cytometry
Klassificering Monoclonal
Klona M-A712
Koncentration 0.5mg/mL
Konjugera Unconjugated
Beskrivning TFR; TFRC; Trfr; TfR1; Transferrin receptor protein 1
Formulering Aqueous buffered solution containing ≤0.09% sodium azide.
Värd art Mouse
Immunogen T-CLL and Jurkat Cells
Reningsmetod Affinity Purified
Kvantitet 0.1 mg
Regulatorisk status RUO
Forskningsdisciplin Immunology
Primär eller sekundär Primary
Målarter Human
Innehåll och lagring Store undiluted at 4°C
Isotyp IgG2a κ
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For Research Use Only.

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