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Transferrin Receptor Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA527739

Additional Details : Weight : 0.01000kg

Product Code. 13441897

  • 3245.00 SEK / 100µL


In stock, ready to ship: 2
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Description

Description

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.
Specifications

Specifications

Transferrin Receptor
Polyclonal
Unconjugated
TFRC
Liquid
TFRC
Recombit fragment corresponding to a region within amino acids 169 and 407 of Human CD71
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
P02786, Q62351
CD71, T9, TFR, TFR1, TR, TRFR, p90, transferrin receptor protein 1
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
22042, 7037
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