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Invitrogen™ C4BPA Monoclonal Antibody (10-07)
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Product Code. 11594543
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Kvantitet:
100 μg
Unit Size:
100µg
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11594543 100 μg 100µg
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Product Code. 11594543 Supplier Invitrogen™ Supplier No. MA182815

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Mouse Monoclonal Antibody

Mouse anti human C4bp monoclonal antibody, clone 051-198.6.3 (10-07), recognizes complement component 4 binding protein (C4bp). There are three variants of C4bp, composed of alpha and beta chains.

There are 3 variants of Complement component 4 binding protein (C4bp), which is composed of alpha and beta chains. The predominant form is a 570 kDa complex of 7 alpha chains and 1 beta chain. The other complexes formed are a 530 kDa homoheptamer of alpha chains or a 500 kDa complex of 6 alpha chains and 1 beta chain. C4bp regulates the activation of the classical complement pathway. It is a cofactor to the C3b/C4b inactivator, crucial to the proteolytic cleavage of C4b and important in cleavage of C3b. C4bp also regulates the C4bC2a complex (C3 convertase), accelerating its degradation by dissociating the complement fragment C2a. Both the C4bp alpha and beta chains interact with anticoagulant protein S and C4bp alpha binds protein S. C4bp is expressed in the blood serum.
TRUSTED_SUSTAINABILITY

Specifications

Antigen C4BPA
Användningsområden ELISA, Flow Cytometry
Klassificering Monoclonal
Klona 10-07
Koncentration 1.15 mg/mL
Konjugera Unconjugated
Formulering BBS with 0.1% sodium azide; pH 8.4
Gen C4BPA
Genaccessionsnr. P04003
Gene Alias AI195242; C4b-binding protein; C4b-binding protein alpha chain; C4bp; C4bpa; complement component 4 binding protein; complement component 4 binding protein alpha; complement component 4 binding protein, alpha; proline-rich protein; PRP; RP11-164O23.4
Gensymboler C4BPA
Värd art Mouse
Immunogen Native human C4 binding protein.
Reningsmetod Protein A
Kvantitet 100 μg
Regulatorisk status RUO
Primär eller sekundär Primary
Gen-ID (Entrez) 722
Målarter Human
Innehåll och lagring Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Produkttyp Antibody
Form Liquid
Isotyp IgG2b
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