Invitrogen™ DDX4 Monoclonal Antibody (2F9H5)

Beskrivning

MA5-15565 targets DDX4 in FACS, IF, IHC, and WB applications and shows reactivity with Human samples. The MA5-15565 immunogen is purified recombinant fragment of human DDX4 expressed in E. Coli. MA5-15565 detects DDX4 which has a predicted molecular weight of approximately 76kDa.

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a homolog of VASA proteins in Drosophila and several other species. The gene is specifically expressed in the germ cell lineage in both sexes and functions in germ cell development. Multiple transcript variants encoding different isoforms have been found for this gene.