missing translation for 'onlineSavingsMsg'
Learn More

Estrogen Receptor alpha Mouse anti-Human, Clone: 1D5, Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MA513191

Additional Details : Weight : 0.01000kg

Product Code. 11304803

  • 5130.00 SEK / 500µL


EU Stock 1
Add to basket

Description

Description

Estrogen Receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptors. The estrogen receptor is a ligand-activated transcription factor, that when bound to estrogen hormone, induces a conformational change that allows dimerization and binding to estrogen response elements (ERE) in DNA. When bound to EREs, ER can positively or negatively regulate gene transcription through the recruitment of coactivator or corepressor proteins. There are two different forms of the estrogen receptor, alpha and beta, encoded by separate genes (ESR1 and ESR2, respectively). Due to alternative RNA splicing, at least 4 estrogen receptor-alpha isoforms are known to exist (Isoform 1 (66 kDa), Isoform 2 (53 kDa), Isoform 3 (47 kDa), Isoform 4 (35 kDa)). Estrogen receptors are widely expressed in different tissue types and are essential for sexual development and reproductive function. They also play a role in other tissues such as bone. Estrogen receptors are involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis.
Specifications

Specifications

Estrogen Receptor alpha
Monoclonal
0.8 mg/mL
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
P03372
ER-alpha, estradiol receptor, estrogen receptor, estrogen receptor alpha delta 3*,4,5,6,7*/819-2 isoform, estrogen receptor alpha delta 4 +49 isoform, estrogen receptor alpha delta 4*,5,6,7*/654 isoform, nuclear receptor subfamily 3 group A member 1
Mouse
IgG1, kappa
500 μL
4° C
Primary
2099
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
1D5
Unconjugated
ESR1
Liquid
ESR1
Recombit human estrogen receptor protein
Protein G
RUO
Antibody
Monoclonal
Human
Videos
Documents