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GSR Mouse anti-Human, Clone: 2B3, Invitrogen™
Mouse Monoclonal Antibody
Brand: Invitrogen LFMA0024
Additional Details : Weight : 0.99000kg
Description
A suggested positive control for this product is HeLa cells.
Glutathione reductase (GR) is a member of pyridine nucleotide-disulfide oxidoreductases, which includes the closely related enzymes thioredoxin reductase, lipoamide dehydrogenase, trypanothione reductase and mercuric ion reductase. GR is a cytoplasmic flavoenzyme widely distributed in aerobic organisms. The dimeric protein is composed of two identical subunits, each containing 1 FAD and 1 redox-active disulfide/dithiol as components of the catalytic apparatus. It plays a role in maintaining glutathione (GSH) in its reduced form by catalyzing the reduction of glutathione disulfide (GSSG) : GSSG + NADPH + H+ to 2GSH + NADP+ In most eukaryotic cells, GR maintains the ratio of [GSH]/[GSSG] elevated, and participates in several vital functions such as the detoxification of reactive oxygen species as well as protein and DNA biosynthesis.Specifications
GSR | |
Monoclonal | |
Unconjugated | |
P00390 | |
GSR | |
Purified, recombit, human glutathione reductase protein expressed in E. coli. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG1 |
ELISA, Immunoprecipitation | |
2B3 | |
GSR | |
GR | |
Mouse | |
Ammonium sulfate precipitation | |
RUO | |
2936 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Liquid |