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Ly-6D Rat anti-Mouse, Unlabeled, Clone: 49-H4, BD
Rat Monoclonal Antibody
Brand: BD Biosciences 557360
Beskrivning
The 49-H4 antibody reacts with the ThB antigen (Ly-6D), which is a 15kDa GPI-anchored protein of the Ly-6 multigene family. ThB has been detected on cortical thymocytes, small sIg- Thy-1- and sIg+ lymphoid cells in the bone marrow, thymic medullary epithelial cells, all epidermal layers (except the stratum corneum), and on peripheral B lymphocytes, but not on peripheral T lymphocytes. It has been noted that there is strain-to-strain variation in the expression of the ThB antigen on splenic B cells, those of strains with the Ly-6.2 haplotype (e.g., AKR, C57BL, DBA/2, SJL, SWR) stain more intensely with anti- ThB reagents than those of Ly-6.1 strains (e.g., A, BALB/c, CBA, C3H/He, NZB), and B cells of hybrids of Ly-6.1 and Ly-6.2 strains stain with intermediate intensity. The proportions of the ThB+ B cells and thymocytes do not differ significantly among strains.
Host Species: Rat
Clone: 49-H4
Isotype: IgG2c
Cross Reactivity: Mouse
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation
Specifikationer
| Ly-6D | |
| Monoclonal | |
| 0.5mg/mL | |
| Lymphocyte antigen 6 complex, locus D; Thb; Thymocyte B-cell antigen; Ly-61 | |
| Rat | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C |
| Flow Cytometry | |
| 49-H4 | |
| Unconjugated | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| BALB/c mouse plasmacytoma MOPC-104E | |
| 0.1 mg | |
| Immunology | |
| Mouse | |
| IgG2c κ |
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