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PON1 Mouse anti-Human, Mouse, Rat, Clone: 17A12, Invitrogen™

Produktkod. 10365650
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Kvantitet:
100 μL
Förpackningsstorlek:
Varje
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10365650 100 μL Varje
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Produktkod. 10365650 Leverantör Invitrogen Leverantörsnummer LFMA0099

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Beskrivning

Mouse Monoclonal Antibody

A suggested positive control for this product is HepG2 cells.

The paraoxonase (PON) gene-family in humans has three members, PON1, PON2, and PON3, aligned next to each other on the long arm of chromosome 7q21.3-22.1. PON1 of these is synthesized primarily in the liver and a portion is secreted into the plasma, where it is associated with high density lipoproteins (HDL). And It hydrolyzes the active metabolites of several other organophosphorus insecticides (e.g., chlorpyrifos oxon, diazoxon), as well as nerve agents such as sarin, soman and VX (lethal nerve agent). The PON1 polymorphism may be responsible for neurodegeneration and considered to be an independent risk factor for Parkinson′s disease.
TRUSTED_SUSTAINABILITY

Specifikationer

Antigen PON1
Användningsområden Western Blot
Klassificering Monoclonal
Klona 17A12
Koncentration 4 mg/mL
Konjugera Unconjugated
Gen PON1
Genaccessionsnr. P27169, P52430, P55159
Gene Alias A esterase 1, Aromatic esterase 1, ESA, PON1
Gensymboler PON1
Värd art Mouse
Immunogen Purified, His-tagged, recombit, human PON1 protein expressed in E. coli.
Reningsmetod Protein G
Kvantitet 100 μL
Regulatorisk status RUO
Primär eller sekundär Primary
Gen-ID (Entrez) 18979, 5444, 84024
Målarter Human, Mouse, Rat
Innehåll och lagring -20° C, Avoid Freeze/Thaw Cycles
Produkttyp Antibody
Form Liquid
Isotyp IgG1
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Produkttitel
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