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Phospho-NMDAR1 (Ser897) Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA539698
Additional Details : Weight : 0.00900kg
Description
NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. Plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors. The ion channels activated by glutamate are divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by kainate and a-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as kainate/AMPA receptors (K/AMPAR). NMDA receptors are among the most studied receptors in neuroscience because they are involved in neuronal cell development and plasticity, a cellular correlate for learning.Specifications
Phospho-NMDAR1 (Ser897) | |
Polyclonal | |
Unconjugated | |
GRIN1 | |
N-methyl-D-aspartate receptor subunit NR1, NMDAR1, NMDAR1, pGluN1 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
14810, 24408, 2902 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
1 mg/mL | |
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4 | |
Q05586, P35438, P35439 | |
GRIN1 | |
A synthetic phosphopeptide derived from human NMDAR1 around the phosphorylation site of Ser897 (R-S-SP-K-D) | |
100 μg | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |