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Invitrogen™ Phospho-Paxillin (Tyr31) Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ 44720G
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Beskrivning
Phospho-Paxillin (Tyr31) Polyclonal Antibody for Western Blot, IHC, ICC/IF
Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. Paxillin associates tightly with FAK and Crk through its SH2 domain. This interaction is independent of the extracellular matrix. Although paxillin was initially discovered in fibroblasts, its phosphorylation may also be important during neurite extension during differentiation.
Specifikationer
| Phospho-Paxillin (Tyr31) | |
| Polyclonal | |
| Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3 | |
| P49023, Q8VI36 | |
| PXN | |
| The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human paxillin that contains tyrosine 31. | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
| Immunohistochemistry, Western Blot, Immunocytochemistry | |
| Unconjugated | |
| PXN | |
| adaptor protein; AW108311; AW123232; FLJ16691; hCG_1778014; I79_001229; myocardial ischemic preconditioning associated protein 7; Pax; PAX-1; PAXI; Paxillin; paxillin a; paxillin alpha; pxn; pxna; testicular tissue protein Li 134; TGFB1I1; transforming growth factor beta 1 induced transcript 1; wu:fw71f12 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 19303, 5829 | |
| -20°C | |
| Liquid |
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