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Phospho-Syk (Tyr323) Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA538335

Additional Details : Weight : 0.00900kg

Product Code. 15525261

  • 4210.00 SEK / 100µg
Estimated Shipment: 06-05-2024
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Description

Description

Syk (spleen tyrosine kinase) is a 635 amino acid protein that contains one protein kinase domain and two SH2 domains. One of several members of the protein kinase superfamily, Syk functions as a positive effector of B cell antigen receptor (CD79)-stimulated responses, coupling CD79 with the movement of one calcium ion through one of two phospho-regulated pathways. Via its ability to influence CD79 activity and to control the movement of calicum through the cell, Syk plays an important role in a variety of cellular responses, including differentiation, phagocytosis, proliferation and B cell development. Syk expression is upregulated in T cell lymphoma, suggesting a possible role for Syk in tumorigenesis. Two isoforms of Syk, designated short and long, exist due to alternative splicing events.
Specifications

Specifications

Phospho-Syk (Tyr323)
Polyclonal
Unconjugated
SYK
Tyrosine-protein kinase SYK, Spleen tyrosine kinase, p72-Syk, SYK
Rabbit
Antigen affinity chromatography
RUO
20963, 25155, 6850
-20°C
Liquid
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
P43405, P48025, Q64725
SYK
A synthetic phosphopeptide derived from human SYK around the phosphorylation site of Tyr323 (N-P-YP-E-P)
100 μg
Primary
Human, Mouse, Rat
Antibody
IgG
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