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SFTPB Precursor Monoclonal Antibody (SPB01 (1-2-A5-9)), Biotin, Invitrogen™
Mouse Monoclonal Antibody
Brand: Invitrogen MA513972
Additional Details : Weight : 0.01000kg
Description
MA5-13972 targets Surfactant Protein B (Precursor) in IF and IHC (P) applications and shows reactivity with Human and Rat samples. The MA5-13972 immunogen is recombit pro-surfactant protein B.
Pulmonary surfactant is a complex mixture of phospholipids and proteins that is secreted from type II cells in alveoli and reduces the surface tension at the alveolar air-liquid interface, providing alveolar stability necessary for normal ventillation. Four distinct proteins isolated from pulmonary surfactant are termed surfactant proteins A, B, C, and D. SP-A (28-36kDa) and SP-D (43kDa) are collagenous carbohydrate-binding proteins, whereas SP-B (8-9kDa) and SP-C (4kDa) are non-collagenous hydrophobic proteins. SP-B is expressed in pulmonary adenocarcinomas with acinar, papillary, bronchioloalveolar, and solid growth patterns. Squamous cell and large cell carcinomas of the lung and nonpulmonary adenocarcinomas do not express SP-B. ProSP-B is glycosylated in the Golgi apparatus and undergoes carboxy- and amino-terminal proteolysis by a cathepsin D-like protease.Specifications
SFTPB Precursor | |
Monoclonal | |
0.2 mg/mL | |
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4 | |
P07988, P22355 | |
SFTPB | |
Recombit pro-surfactant protein B | |
500 μL | |
Primary | |
Human, Rat | |
Antibody | |
IgG2a κ |
Immunofluorescence, Immunohistochemistry (Paraffin) | |
SPB01 (1-2-A5-9) | |
Biotin | |
SFTPB | |
18 kDa pulmonary-surfactant protein, 6 kDa protein,pulmonary surfactant-associated protein B, pulmonary surfactant-associated proteolipid SPL(Phe) | |
Mouse | |
Protein A | |
RUO | |
192155, 6439 | |
4° C | |
Liquid |